No liquid scintillation cocktail is required, as scintillant is already embedded in the walls of the microplate.
In assays using scintillation-embedded plates, separation of "positive" and "negative" signal from the radiochemical is achieved by designing the assay in such a way that the radiochemical is associated with the walls or base of the microplate (and therefore able to interact with the scintillant) under given conditions.
The energy absorbed through the scintillators produces excited states of the electrons, which decay to the ground state and produce a light pulse characteristic for the scintillator.
Glass provides unparalleled optical clarity (good visibility) and is chemically inert, making it suitable for use with aggressive reagents and solvents.
Good mixing is needed in vials as well as microtiter plates.
Many plates and vials exist, and the choice of what type of vial or plate to use will depend on factors such as volume, chemical resistance, safety, and performance in combination with the cocktail of choice.
Liquid scintillation counting (LSC) is the standard laboratory method to quantify the radioactivity of low energy radioisotopes, mostly beta-emitting and alpha-emitting isotopes.
This makes the QUANTULUS Liquid Scintillation Spectrometer a good choice for Carbon-14-dating.